#AcneSerum
Original price was: ฿490.00.฿368.00Current price is: ฿368.00.
Quantity
Nectapharma Bioactive Acne Clear Serum
Original price was: ฿490.00.฿368.00Current price is: ฿368.00.
30 ml
Acne Serum is an acne treatment serum formulated for sensitive skin. It is designed to specifically care for acne-prone skin and targets all 4 key mechanisms of acne formation at the source.
It also helps maintain skin hydration, preventing dryness and peeling. Clinically tested under dermatological supervision and proven by real users to show visible acne reduction within 14 days of use.
Original price was: ฿490.00.฿368.00Current price is: ฿368.00.
In stock
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`As seen on Social Media`
TIKTOK
Invested over 600,000 THB in research and development to formulate Acne Serum, Nectapharma’s most advanced acne treatment serum 👨🔬
X
I feel like nowadays, skincare brands for acne should really focus on research and real, evidence-based ingredients. Nectapharma, for example, invested over 600,000 THB in real-user testing and research, which shows that they are genuinely attentive to consumers. At its core, this Acne Serum is especially suitable for acne-prone skin, focusing directly on acne concerns with a science-driven approach.
Acne support serum that helps strengthen skin and restore skin barrier health! @nectapharma is specially formulated for acne-prone and oily skin types 🤍 #AcneClearSerum #BIOACTIVEAcneClearSerum #Nectapharma
It really exists—a serum that helps with acne ✨ And it’s also gentle, non-irritating!
TIKTOK
The right ingredients for acne-prone skin ✨
Found it—the all-in-one solution for acne-prone skin ✨ Bioactive Acne Clear Serum from Nectapharma is now my favorite💕 #AcneClearSerum #BIOACTIVEAcneClearSerum #Nectapharma
TIKTOK
Acne Serum has been intensively tested on real users under clinical conditions by dermatology experts 👨🔬
Recommended from the heart by someone who has experienced acne #AcneClearSerum ✨ Thank you for the review from Keenloval 🙏
X
I don’t get acne often, but I still always use acne serum because it helps prevent new breakouts. Lately I’ve been using the green bottle from Nectapharma—no new pimples at all. It also helps reduce old acne marks and clogged pores, adds hydration, and makes my skin less oily. Dark spots also look lighter. Really loving it! ✨
Say goodbye to acne-prone skin and welcome clear skin in 2026 with this must-have item ✨ I’m really loving it right now! #AcneClearSerum #BIOACTIVEAcneClearSerum #Nectapharma
TIKTOK
This acne serum has a 100/10 texture and really helps with acne. I can honestly say I’ll keep using it long-term 🙆🏻♀️🤍 #AcneClearSerum #BIOACTIVEAcneClearSerum #Nectapharma #Nectapharma @nectapharma
TIKTOK
Good skin doesn’t come easy—but it’s not that hard either, because of this one! ✨
TIKTOK
Acne Serum — does it cause purging?! 👀 This video has the answer.
Why invest as much as 600,000 THB 💸 just to test a single skincare product? 🤔⁉
`Trusted by Real Users
Bioactive Acne Clear Serum`
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nuanpr
21 Apr 2025 | 00:00
The packaging quality is excellent. The serum has a lightweight texture that absorbs easily into the skin.
First impression after using it once is very positive. It feels like it helps gradually balance and improve the skin over time, until it can be used comfortably both morning and night.
numneung2527
09 Apr 2025 | 08:15
Received the product completely and delivery was fast. The store has many items.
I ordered BIOACTIVE ACNE CLEAR SERUM—it absorbs quickly.
After use, active breakouts seem to calm down and acne marks also look lighter. I’m not 100% sure, but I’ve been applying it morning and night, and pimples and small bumps seem to reduce.
Good quality, exceeds expectations for the price. Promotions are also too good to resist 🤣
n*****e
05 May 2025 | 08:00
I’m really impressed with the product quality. It’s very well made in terms of texture, absorption, and overall effectiveness.
After using it, I feel like I’m getting fewer breakouts. If anything does appear, it’s just very small clogged bumps and very minimal. It absorbs well into the skin—really not disappointing at all.
`Bioactive Acne Clear Serum,
with results confirmed by real users`
Acne serum for sensitive skin, designed to suit all skin types. It works as both an acne-targeting serum and a skin-repairing treatment, helping restore smooth, hydrated, and healthy-looking skin sustainably. It is a suitable choice for those looking for a gentle yet effective acne serum.
Clinical study under dermatological supervision by Dermscan Asia on 21 Asian volunteers over 54 days showed:
- 100% of participants had reduced total acne count from day 14
- 71% of participants experienced reduced skin oiliness
- 100% of participants had no dryness or peeling, with improved skin hydration
- 90% of participants reported smoother skin
- 95% of participants felt acne marks had faded
- Overall acne severity (Global Acne Severity Scale) was reduced
- Non-comedogenic (does not clog pores)
- Non-acnegenic (does not cause new acne)
Acne reduction serum targeting all acne formation pathways
Acne serum from Nectapharma is specifically designed to directly address acne problems at their root. It helps manage all types of acne, including inflammatory acne, clogged pores, and small bumps, by targeting all 4 key mechanisms of acne formation.
Controls excess oil production.
Excess oil production is one of the main causes of acne. This acne serum helps regulate sebum secretion from the sebaceous glands, reducing oily skin and effectively lowering the risk of clogged pores.
Gently exfoliates skin cells.
The skin naturally undergoes cell turnover. However, in some cases where this process becomes imbalanced, dead skin cells can accumulate, leading to clogged pores and acne.
This acne serum helps promote the gentle shedding of dead skin cells, reducing the risk of clogged pores and helping prevent recurring acne breakouts. It is suitable for those looking for a gentle acne treatment serum for clogged pores.
Reduces the accumulation of acne-causing bacteria (C. acnes).
The accumulation of acne-causing bacteria (C. acnes) can trigger inflammation and cause acne to worsen.
Therefore, inhibiting these bacteria is an important step in reducing the number and severity of acne breakouts, as well as helping to prevent recurring acne.
Reduces inflammation.
When acne occurs and C. acnes bacteria accumulate, the skin enters an inflammatory state that can cause redness, swelling, pain, and post-acne marks after healing.
This acne serum helps soothe irritated, acne-prone skin and supports faster calming of breakouts, making it an effective solution for inflammatory acne care.
Key ingredients in acne serum with research-supported concentrations
One of the key strengths of Bioactive Acne Clear Serum is the use of active ingredients at research-backed concentrations, designed to deliver visible results in acne, including inflammatory acne, clogged pores, post-acne marks, and skin hydration.
AHA (Alpha Hydroxy Acids) 2%
Helps gently exfoliate dead skin cells without causing dryness or peeling. Suitable for reducing small bumps and helping minimize pore congestion, making it effective for acne-prone skin care. [1]
Niacinamide 5%
Zinc PCA 1%
Helps control excess oil on the skin and reduce the accumulation and growth of acne-causing bacteria (C. acnes). [10]
`All Ingrediets of Bioactive Acne Clear Serum`
Water, Niacinamide, Glycereth-26, Camellia Sinensis Leaf Extract, Zinc PCA, Centella Asiatica Extract, Propanediol, Propylene Glycol, Polyacrylate Crosspolymer-11, Garcinia Mangostana Peel Extract, Phenoxyethanol, Pentylene Glycol, 1,2-Hexanediol, Citric Acid, Glycolic Acid, Lactic Acid, Malic Acid, Prunus Armeniaca Fruit Extract, Psidium Guajava Fruit Extract, Vitis Vinifera Fruit Extract, Mangifera Indica Fruit Extract, Prunus Persica Fruit Extract, Rubus Idaeus Fruit Extract, Fragaria Ananassa Fruit Extract, Triethylene Glycol, Dipotassium Glycyrrhizinate, Sodium Hydroxide, Magnolia Officinalis Bark Extract, Paeonia Albiflora Root Extract, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Sorbate, Ehtylhexylglycerin
Alpha-Mangostin 0.67%
Helps reduce inflammation and inhibit acne-causing bacteria growth, leading to a reduction in both comedonal and inflammatory acne without causing irritation [5, 6]
Green Tea EGCG 1%
Helps reduce acne inflammation, control excess sebum production, and inhibit the growth of acne-causing bacteria [7]
Centella Asiatica 1%
Helps soothe inflammation caused by acne, calms irritated skin, and provides hydration to the skin [8, 9]
Hymagic™-4D
Helps deeply hydrate the skin and reduce transepidermal water loss (TEWL). It consists of four molecular weights of hyaluronic acid, designed to effectively penetrate multiple skin layers for optimal hydration [11]
Apply the acne treatment serum all over the face, avoiding the eye area.
Start using it in the evening every other night. Once the skin has adapted, gradually increase to twice daily, morning and evening.
It is recommended to use together with a moisturizer and a sunscreen with at least SPF 30 for best results.
- pH 5.44
- Dermatologist tested
- Non-comedogenic
- Non-acnegenic
- Free from fragrance, alcohol, parabens, silicones, mineral oil, and artificial colorants
- Cruelty-free (no animal testing)
30 ml
`Frequently Asked Questions
Bioactive Acne Clear Serum`
A: It can help manage all types of acne, including whiteheads, blackheads, inflammatory acne, hormonal acne, and comedones (skin texture bumps).
Clogged pores (comedonal acne)
Helps gently reduce pore blockage and supports mild exfoliation to clear congested skin without irritation. It works as an acne-clearing serum designed to unclog pores and improve overall skin clarity.
Inflammatory acne
Helps reduce inflammation and soothe irritated skin, supporting faster calming of breakouts with less visible marks. It is suitable for those looking for an acne soothing and repair serum.
Recurring acne
Helps target acne at the source by controlling excess oil and reducing acne-causing bacteria buildup, helping prevent new breakouts over time. It functions as both an oil-control and acne-prevention serum for long-term skin balance.
A: Nectapharma Acne Serum is formulated to be gentle on the skin, so the chance of purging is very low. However, in some cases it may still occur.
Purging usually happens when a product speeds up skin cell turnover, causing existing microcomedones (hidden clogged pores) under the skin to surface more quickly.
If it occurs, it is typically seen within the first 2–6 weeks, depending on individual skin condition, and often appears in areas where acne has previously occurred.
It is recommended to continue consistent use to allow the skin to gradually adapt and to help reduce future breakouts in the long term.
A: Acne Serum is suitable for sensitive skin. This acne treatment serum has been tested under dermatological supervision by Dermscan Asia and has been shown to be non-irritating, non-comedogenic, and non-acnegenic.
A: It can be used together. It is recommended to apply the acne spot treatment first, then follow with the acne serum.
However, if the spot treatment belongs to the retinoid group such as Tretinoin and is used at night, it is recommended to use the acne serum in the morning instead.
Once the skin has adapted, both can be used in the same routine. However, extra attention should be given to skin hydration, and results may vary depending on individual skin conditions.
References
1
Karwal, K., & Mukovozov, I. (2023). Topical AHA in Dermatology: Formulations, Mechanisms of Action, Efficacy, and Future Perspectives. Cosmetics, 10(5), 131. https://doi.org/10.3390/cosmetics10050131
2
Draelos, Z. D., Matsubara, A., & Smiles, K. (2006). The effect of 2% niacinamide on facial sebum production. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 8(2), 96–101. https://doi.org/10.1080/14764170600717704
3
Khodaeiani, E., Fouladi, R. F., Amirnia, M., Saeidi, M., & Karimi, E. R. (2013). Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris. International journal of dermatology, 52(8), 999–1004. https://doi.org/10.1111/ijd.12002
4
Navarrete-Solís, J., Castanedo-Cázares, J. P., Torres-Álvarez, B., Oros-Ovalle, C., Fuentes-Ahumada, C., González, F. J., Martínez-Ramírez, J. D., & Moncada, B. (2011). A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma. Dermatology research and practice, 2011, 379173. https://doi.org/10.1155/2011/379173
5
Lueangarun, S., Sriviriyakul, K., Tempark, T., Managit, C., & Sithisarn, P. (2019). Clinical efficacy of 0.5% topical mangosteen extract in nanoparticle loaded gel in treatment of mild-to-moderate acne vulgaris: A 12-week, split-face, double-blinded, randomized, controlled trial. Journal of cosmetic dermatology, 18(5), 1395–1403. https://doi.org/10.1111/jocd.12856
6
Krisdaphong, T., & Jedsadapaisid, S. (2012). Antimicrobial activity of Garcinia mangostana extract for anti-acne therapy. IFSCC Magazine, 15(1), 9–12.
7
Yoon, J. Y., Kwon, H. H., Min, S. U., Thiboutot, D. M., & Suh, D. H. (2013). Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes. The Journal of investigative dermatology, 133(2), 429–440. https://doi.org/10.1038/jid.2012.292
8
Aszrin, Farashakira & Adam, Siti & Abdul Mutalib, Maisarah & Tang, Hooi & Tang, Shirley. (2024). An overview of Centella asiatica and its therapeutic applications. Life Sciences, Medicine and Biomedicine. 8. 10.28916/lsmb.8.1.2024.146.
9
Shen, X., Guo, M., Yu, H., Liu, D., Lu, Z., & Lu, Y. (2019). Propionibacterium acnes related anti-inflammation and skin hydration activities of madecassoside, a pentacyclic triterpene saponin from Centella asiatica. Bioscience, biotechnology, and biochemistry, 83(3), 561–568. https://doi.org/10.1080/09168451.2018.1547627
10
Solabia Group. (n.d.). Zincidone®: Physiological seboregulator. Retrieved from https://www.solabia.com/cosmetics/product/zincidone/
11
Bloomage Biotech. (n.d.). Hymagic™-4D. Retrieved from https://www.bloomagebioactive.com/En/Product/Info/10920
`Product Philosophy`
Research-Backed
Trademarked Ingredients, Strict Manufacturing Standards, Clinically Proven Results, Safe, Transparent, Trusted by Doctors and Pharmacists.
Thoughtfully Formulated
All of our products are developed by a highly experienced team of pharmacists, and formulated based on multiple scientific studies. Every claim is supported by scientific research.
Trusted Quality
Every formula is carefully developed to ensure that each ingredient works together effectively, providing targeted support while addressing the root causes of the problem.
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